Immunologist wins "Breakthrough Prize" for innovative cancer treatment

Michel Sadelain, a French and Canadian scientist, has won the Breakthrough Prize for his groundbreaking work in CAR T-cell therapy, a highly effective treatment for blood cancers.

Initially met with skepticism, Sadelain faced challenges in securing grants and attracting graduate students to his lab.

His pioneering approach involves genetically reprogramming T-cells to target and destroy specific cancer cells.

This has led to the development of several approved CAR-T cell therapies in the US, with numerous trials ongoing. The treatment, while promising, carries risks and comes with a high cost, often exceeding $500,000.

Sadelain envisions future advancements, including targeting solid cancers and tackling conditions like HIV (human immunodeficiency virus).

Efforts to reduce costs and improve efficiency through innovations like stem cell manufacturing are underway.